lymphnodcs Diagnosis - confirmed by demonstration of microfilariae in skin snips, or cornea or anterior chamber (using slit lamp), or of adull worms i

lymphnodcs Diagnosis - confirmed by demonstration of microfilariae in skin snips, or cornea or anterior chamber (using slit lamp), or of adull worms in aubcutaneous nodules Drug tretment • Suramin kills adutl worms, also DEC or ivemectin Melioidosis • It is caused by Psaudomonas pseudomallci, a Gram-negativs bacillus hur i widey in solland surface-water ol paddy and other fields Man usually acquires Infection through resciratory iract or skin Clinical manifestations vary frorn aubclinical dsesse to overwhelming infections, and practically every organ can be aflacled Diagnosis - Blood culture and scrology Treatment - n sepicemic Infection, comoination of co-tilmaxozole, dOxycycline and chlormphenicol other useful dugs are caltazidime. carumonam and impenam Pinia Non-venereal apirochatal infection caused by Treponema caralcum Transmission by direct contagion from infectious skin lesiors Begins at inoculation site by a small papule that progresses to erythematoua plaques in several months Erytherretous squamous patches develop later, mainly on extremities. face and neck Tertiary stage of the disease is characterised by depigmented or atrophic lessons ol the skin often of the legs wilh hyperkeratosls of ihe soles Treatment - Single dose of benzathine paniclllln 1 5 g IM Zoonoses